Deciphering the mechanisms of toxicity

Published on 13 October 2025

The CIBEST team has expertise in both chemistry and cellular biology. Our research is thus motivated by the understanding of the chemical mechanisms and the resulting biochemical consequences underlying toxicological events. The use of chemical properties of organic compounds and biomolecules is also key to the design of diagnostic and therapeutic tools. In order to collect relevant data, suitable models at the molecular level like isolated DNA or at the cellular level are necessary.

Oxidative stress

Interaction metals/peptides

UV and DNA damage

DNA adducts

DNA repair

DNA Epigenetic modifications

Advanced cellular models

Mixture effects

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Alternative and Atomic Energies Agency

CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.

Molecular Systems and nanoMaterials for Energy and Health - UMR 5819 CEA-CNRS-UGA-Grenoble INP

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Deciphering the mechanisms of toxicity

Highlights : (13 documents)

PhD Theses defended on this topic :

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Molecular Systems and nanoMaterials for Energy and Health - UMR 5819 CEA-CNRS-UGA-Grenoble INP

Molecular Systems and nanoMaterials for Energy and Health Laboratory (SyMMES)

Design of molecular architectures and electronic processes team (CAMPE)

Chemistry Interface Biology for environment, health and toxicology team (CIBEST)

CREAB team

Synthesis, Structure and Properties of Functional Materials team

In the same section :

Deciphering the mechanisms of toxicity

Highlights : (13 documents)

PhD Theses defended on this topic :

Browse the site

Alternative and Atomic Energies Agency

Browse the portal