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Our work confirms the risk of photosensitization in the event of sun exposure in the presence of polycyclic aromatic hydrocarbons (PAHs). The decrease in PAH metabolism by UV rays, which has never been described, induces a delay in the accumulation of DNA damage, but only the metabolised PAHs are eliminated from the skin. Exposure to UV could therefore prolong the duration of exposure in tissues.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.