Over the years, our work on UV radiation and photobiology has enabled us to highlight a number of results, such as the induction of mutagenic damage by UVA, or a better understanding of skin carcinogenesis mechanisms (enabling us to adjust photo-protection messages). We also developed innovative methods such as the assessment of DNA damage by non invasive urinary analyses, which were applied to clinical studies showing that careful application of sunscreen does indeed protect DNA.
Recently, we extended our work to blue light, already known to be involved in photoaging and pigmentation. We could establish that blue light diminishes the ability of cells to eliminate UV-induced damage to DNA, revealing the importance of taking the whole solar spectrum for photo-protection consideration.
