Job description:
The InSiBio (
In Situ Biosensors) project aims to develop interferometric fiber optic biosensors for in situ molecular diagnostics. The post-doc will be involved in all project tasks. He/She will participate in the design and preparation of multifiber assemblies in G. Laffont's team at List/LSPM (Laboratoire des Sciences des Procédés et des Matériaux, CEA-Saclay). He/She will characterize the interferometric responses of the cavities developed using the interrogation systems available at List/LSPM. He/She will then continue to characterize the prototypes in terms of sensitivity and resolution at SYMMES (Systèmes Moléculaires et nanoMatériaux pour l'Energie et la Santé, CEA Grenoble), using an existing optical setup that will also be used for biological validation. He/She will contribute to the development of a new optical setup and to the elaboration of a methodology dedicated to surface multi-functionalization in collaboration with G. Nonglaton from Leti/DTBS (Département des Technologies pour la Biologie et la Santé), he/she will contribute to the development of a new optical assembly and a methodology dedicated to surface multi-functionalization. Finally, he/she will participate in the proof-of-concept of multiplexed biodetection at SyMMES.
Environment:
The post-doc will benefit from a high-level scientific environment to carry out his/her activity. In particular, he/she will benefit from List/LSPM's expertise in fiber optic sensors and 3D printing of interferometric structures at the ends of optical fibers using two-photon polymerization. He/She will be able to produce the special fibers required for the project, thanks to privileged access to a fiber-design facility in an academic laboratory. The post-doc will benefit from SyMMES' expertise in optical instrumentation for the development of a new optical setup dedicated to the functionalization of fibers assemblies. He/She will also benefit from SyMMES' experience in the field of biology, in order to carry out the detection of model biomolecules. He/She will have access to CEA-Leti/DTBS's Surface Chemistry platform for controlled and automated vapor deposition of photosensitive silanes. Access to characterization equipment at CEA Grenoble's Nano-Characterization platform (XPS, AFM, MIR-IR) will complement the offerings of the Surface Chemistry platform (drop angle, zeta potential, QCM-D, fluorescence scanner) to characterize the physico-chemical properties of deposits.
https://www.symmes.fr/
https://www.leti-cea.fr/cea-tech/leti/Pages/Accueil.aspx
https://list.cea.fr/fr/
Information:
Contact:
Élodie Bidal tart and duration of post-doctorate: recruitment possible from now until March 2024 for a renewable period of 1 year
Location: CEA, Grenoble, scientific polygon
https://www.cea.fr/Pages/le-cea/les-centres-cea/grenoble.aspx
Laboratory:
SyMMES Team:
CREAB
Required documents for candidates: CV, cover letter, recommendation letter(s)
Profile: Optician with experience in biochemistry and/or chemistry, possibly in the field of biosensors
Skills required: Experimental and/or theoretical optics, Taste for chemistry and biochemistry, Experience in simulation would be appreciated.
Specificity: Missions on two sites: position based at CEA-Grenoble and frequent travel to CEA-Saclay to be expected (several one-week missions for fiber design).