Thierry DOUKI

Publication List

 

1. Original Research Articles

(1)           von Koschembahr, A., Youssef, A., Beal, D., Gudimard, L., Giot, J. P. and Douki, T. (2020) Toxicity and DNA repair in normal human keratinocytes co-exposed to benzo[a]pyrene and sunlight. Toxicol In Vitro 63, 104744.

(2)           von Koschembahr, A., Youssef, A., Beal, D., Bourgart, E., Rivier, A., Marques, M., Leccia, M. T., Giot, J. P., Maitre, A. and Douki, T. (2020) Metabolism and genotoxicity of polycyclic aromatic hydrocarbons in human skin explants: mixture effects and modulation by sunlight. Arch Toxicol 94, 495–507.

(3)           Taylor, W., Camilleri, E., Craft, D. L., Korza, G., Rocha Granados, M., Peterson, J., Szczpaniak, R., Weller, S. K., Moeller, R., Douki, T., Mok, W. W. K. and Setlow, P. (2020) DNA damage Kills Bacterial Spores and Cells Exposed to 222 nm UV Radiation. Appl Environ Microbiol 86, e03039-03019.

(4)           Pollet, M., Shaik, S., Mescher, M., Frauenstein, K., Tigges, J., Braun, S. A., Sondenheimer, K., Kaveh, M., Bruhs, A., Meller, S., Homey, B., Schwarz, A., Esser, C., Douki, T., Vogel, C. F. A., Krutmann, J. and Haarmann-Stemmann, T. (2020) Correction to: The AHR represses nucleotide excision repair and apoptosis and contributes to UV-induced skin carcinogenesis. Cell Death Differ 27, 403.

(5)           Lecureur, V., Monteil, C., Jaguin, M., Cazier, F., Preterre, D., Corbiere, C., Gosset, P., Douki, T., Sichel, F. and Fardel, O. (2020) Comparative study on gene expression profile in rat lung after repeated exposure to diesel and biodiesel exhausts upstream and downstream of a particle filter. Environ Pollut 266, 115264.

(6)           Josse, G., Gravier, E. and Douki, T. (2020) Method for the accurate determination of the DNA protection factor of sun protection products. Brit. J. Dermatol. 183, 178-179.

(7)           Ikehata, H., Mori, T., Kamei, Y., Douki, T., Cadet, J. and Yamamoto, M. (2020) Wavelength- and Tissue-dependent Variations in the Mutagenicity of Cyclobutane Pyrimidine Dimers in Mouse Skin. Photochem. Photobiol. 96, 94-104.

(8)           Frances-Monerris, A., Hognon, C., Douki, T. and Monari, A. (2020) Photoinduced DNA Lesions in Dormant Bacteria. The Peculiar Route Leading to Spore Photoproduct Characterized by Multiscale Molecular Dynamics. Chem. Eur. J..

(9)           Dussert, F., Arthaud, P. A., Arnal, M. E., Dalzon, B., Torres, A., Douki, T., Herlin, N., Rabilloud, T. and Carriere, M. (2020) Toxicity to RAW264.7 Macrophages of Silica Nanoparticles and the E551 Food Additive, in Combination with Genotoxic Agents. Nanomaterials (Basel) 10.

(10)         Douki, T. (2020) Pyrimidine (6‐4) pyrimidone photoproducts in UVA‐irradiated DNA: photosensitization or photoisomerization? ChemPhotoChem 4, 294-299.

(11)         Youssef, A., von Koschembahr, A., Caillat, S., Corre, S., Galibert, M. D. and Douki, T. (2019) 6-Formylindolo[3,2-b]carbazole (FICZ) is a Very Minor Photoproduct of Tryptophan at Biologically Relevant Doses of UVB and Simulated Sunlight. Photochem. Photobiol. 95, 237-243.

(12)         Dorier, M., Tisseyre, C., Dussert, F., Beal, D., Arnal, M. E., Douki, T., Valdiglesias, V., Laffon, B., Fraga, S., Brandao, F., Herlin-Boime, N., Barreau, F., Rabilloud, T. and Carriere, M. (2019) Toxicological impact of acute exposure to E171 food additive and TiO2 nanoparticles on a co-culture of Caco-2 and HT29-MTX intestinal cells. Mutat Res 845, 402980.

(13)         Bourgart, E., Persoons, R., Marques, M., Rivier, A., Balducci, F., von Koschembahr, A., Beal, D., Leccia, M. T., Douki, T. and Maitre, A. (2019) Influence of exposure dose, complex mixture and ultraviolet radiation on skin absorption and bioactivation of polycyclic aromatic hydrocarbons ex vivo. Archives of Toxicology 93, 2165-2184.

(14)         Bourgart, E., Barbeau, D., Marques, M., von Koschembahr, A., Beal, D., Persoons, R., Leccia, M. T., Douki, T. and Maitre, A. (2019) A realistic human skin model to study benzo[a]pyrene cutaneous absorption in order to determine the most relevant biomarker for carcinogenic exposure. Arch. Toxicol. 93, 81-93.

(15)         Banyasz, A., Balanikas, E., Martinez-Fernandez, L., Baldacchino, G., Douki, T., Improta, R. and Markovitsi, D. (2019) Radicals Generated in Tetramolecular Guanine Quadruplexes by Photoionization: Spectral and Dynamical Features. J. Phys. Chem. B 123, 4950-4957.

(16)         Young, A. R., Greenaway, J., Harrison, G. I., Lawrence, K. P., Sarkany, R., Douki, T., Boyer, F., Josse, G., Questel, E., Monteil, C. and Rossi, A. B. (2018) Sub-optimal Application of a High SPF Sunscreen Prevents Epider-mal DNA Damage in Vivo. Acta Derm. Venereol. 98, 880-887.

(17)         von Koschembahr, A., Youssef, A., Béal, D., Calissi, C., Bourgart, E., Marques, M., Leccia, M.-T., Giot, J.-P., Maitre, A. and Douki, T. (2018) Solar simulated light exposure alters metabolization and genotoxicity induced by benzo[a]pyrene in human skin. Sci. Rep. 8, 14692.

(18)         Pollet, M., Shaik, S., Mescher, M., Frauenstein, K., Tigges, J., Braun, S. A., Sondenheimer, K., Kaveh, M., Bruhs, A., Meller, S., Homey, B., Schwarz, A., Esser, C., Douki, T., Vogel, C. F. A., Krutmann, J. and Haarmann-Stemmann, T. (2018) The AHR represses nucleotide excision repair and apoptosis and contributes to UV-induced skin carcinogenesis. Cell Death Differ. 25, 1823-1836.

(19)         Lawrence, K. P., Douki, T., Sarkany, R. P. E., Acker, S., Herzog, B. and Young, A. R. (2018) The UV/visible radiation boundary region (385 – 405 nm) damages skin cells and induces “dark” cyclobutane pyrimidine dimers in human skin in vivo. Sci. Rep. 8, 12722.

(20)         Josse, G., Douki, T., Le Digabel, J., Gravier, E. and Questel, E. (2018) The use of suction blisters to measure sunscreen protection against UVR-induced DNA damage. J. Photochem. Photobiol. B: Biol. 179, 1-6.

(21)         Ikehata, H., Mori, T., Douki, T., Cadet, J. and Yamamoto, M. (2018) Quantitative analysis of UV photolesions suggests that cyclobutane pyrimidine dimers produced in mouse skin by UVB are more mutagenic than those produced by UVC. Photochem. Photobiol. 17, 404-413.

(22)         Hosseini, M., Dousset, L., Mahfouf, W., Serrano-Sanchez, M., Redonnet-Vernhet, I., Mesli, S., Kasraian, Z., Obre, E., Bonneu, M., Claverol, S., Vlaski, M., Ivanovic, Z., Rachidi, W., Douki, T., Taieb, A., Bouzier-Sore, A. K., Rossignol, R. and Rezvani, H. R. (2018) Energy Metabolism Rewiring Precedes UVB-Induced Primary Skin Tumor Formation. Cell Rep. 23, 3621-3634.

(23)         Douki, T., Corbiere, C., Preterre, D., Martin, P. J., Lecureur, V., Andre, V., Landkocz, Y., Pottier, I., Keravec, V., Fardel, O., Moreira-Rebelo, S., Pottier, D., Vendeville, C., Dionnet, F., Gosset, P., Billet, S., Monteil, C. and Sichel, F. (2018) Comparative study of diesel and biodiesel exhausts on lung oxidative stress and genotoxicity in rats. Environ. Pollut. 235, 514-524.

(24)         Berube, R., Drigeard Desgarnier, M. C., Douki, T., Lechasseur, A. and Rochette, P. J. (2018) Persistence and Tolerance of DNA Damage Induced by Chronic UVB Irradiation of the Human Genome. J. Invest. Dermatol. 138, 405-412.

(25)         Biola-Clier, M., Beal, D., Caillat, S., Libert, S., Armand, L., Herlin-Boime, N., Sauvaigo, S., Douki, T. and Carriere, M. (2017) Comparison of the DNA damage response in BEAS-2B and A549 cells exposed to titanium dioxide nanoparticles. Mutagenesis 32, 161-172.

(26)         Banyasz, A., Martinez-Fernandez, L., Balty, C., Perron, M., Douki, T., Improta, R. and Markovitsi, D. (2017) Absorption of Low-Energy UV Radiation by Human Telomere G-Quadruplexes Generates Long-Lived Guanine Radical Cations. J. Am. Chem. Soc. 139, 10561-10568.

(27)         Sauvaigo, S., Sarrazy, F., Batal, M., Caillat, S., Pitiot, B., Mouret, S., Clery-Barraud, C., Boudry, I. and Douki, T. (2016) Impact of topical application of sulfur mustard on mice skin and distant organs DNA repair enzyme signature. Toxicol. Lett. 241, 71-81.

(28)         Gomez-Mendoza, M., Banyasz, A., Douki, T., Markovitsi, D. and Ravanat, J. L. (2016) Direct Oxidative Damage of Naked DNA Generated upon Absorption of UV Radiation by Nucleobases. J. Phys. Chem. Lett. 7, 3945-3948.

(29)         Genies, C., Jullien, A., Lefebvre, E., Revol, M., Maitre, A. and Douki, T. (2016) Inhibition of the formation of benzo a pyrene adducts to DNA in A549 lung cells exposed to mixtures of polycyclic aromatic hydrocarbons. Toxicol. Vitro 35, 1-10.

(30)         Douki, T. (2016) Relative Contributions of UVB and UVA to the Photoconversion of (6-4) Photoproducts into their Dewar Valence Isomers. Photochem. Photobiol. 92, 587-594.

(31)         Barbier, E., Lagorce, A., Hachemi, A., Dutertre, M., Gorlas, A., Morand, L., Saint-Pierre, C., Ravanat, J. L., Douki, T., Armengaud, J., Gasparutto, D., Confalonieri, F. and Breton, J. (2016) Oxidative DNA Damage and Repair in the Radioresistant Archaeon Thermococcus gammatolerans. Chem. Res. Toxicol. 29, 1796-1809.

(32)         Banyasz, A., Esposito, L., Douki, T., Perron, M., Lepori, C., Improta, R. and Markovitsi, D. (2016) Effect of C5-Methylation of Cytosine on the UV-Induced Reactivity of Duplex DNA: Conformational and Electronic Factors. J. Phys. Chem. B 120, 4232-4242.

(33)         Abou-Hamdan, M., Gardette, B., Cadet, J., Gharib, B., De Reggi, M., Douki, T. and Triantaphylides, C. (2016) Molecular hydrogen attenuates radiation-induced nucleobase damage to DNA in aerated aqueous solutions. Int. J. Radiat. Biol. 92, 536-541.

(34)         Premi, S., Wallisch, S., Mano, C. M., Weiner, A. B., Bacchiocchi, A., Wakamatsu, K., Bechara, E. J. H., Halaban, R., Douki, T. and Brash, D. E. (2015) Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure. Science 347, 842-847.

(35)         Panitz, C., Horneck, G., Rabbow, E., Rettberg, P., Moeller, R., Cadet, J., Douki, T. and Reitz, G. (2015) The SPORES experiment of the EXPOSE-R mission: Bacillus subtilis spores in artificial meteorites. Int. J. Astrobiol. 14, 105-114.

(36)         Mouret, S., Wartelle, J., Batal, M., Emorine, S., Bertoni, M., Poyot, T., Clery-Barraud, C., El Bakdouri, N., Peinnequin, A., Douki, T. and Boudry, I. (2015) Time course of skin features and inflammatory biomarkers after liquid sulfur mustard exposure in SKH-1 hairless mice. Toxicol. Lett. 232, 68-78.

(37)         Forestier, A., Douki, T., De Rosa, V., Beal, D. and Rachidi, W. (2015) Combination of A beta Secretion and Oxidative Stress in an Alzheimer-Like Cell Line Leads to the Over-Expression of the Nucleotide Excision Repair Proteins DDB2 and XPC. Int. J. Mol. Sci. 16, 17422-17444.

(38)         Douki, T., Rebelo-Moreira, S., Hamon, N. and Bayle, P. A. (2015) DNA Photochemistry: Geometrically Unconstrained Pyrimidine (6-4) Pyrimidone Photoproducts Do Photoisomerize. Org. Lett. 17, 246-249.

(39)         Douki, T., Meador, J. A., Berard, I. and Wack, A. (2015) N4-Methylation of Cytosine Drastically Favors the Formation of (6-4) Photoproducts in a TCG Context. Photochem. Photobiol. 91, 102-108.

(40)         Batal, M., Rebelo-Moreira, S., Hamona, N., Bayle, P. A., Mouret, S., Clery-Barraud, C., Boudry, I. and Douki, T. (2015) A guanine-ethylthioethyl-glutathione adduct as a major DNA lesion in the skin and in organs of mice exposed to sulfur mustard. Toxicol. Lett. 233, 1-7.

(41)         Bacqueville, D., Douki, T., Duprat, L., Rebelo-Moreira, S., Guiraud, B., Dromigny, H., Perier, V., Bessou-Touya, S. and Duplan, H. (2015) A new hair follicle-derived human epidermal model for the evaluation of sunscreen genoprotection. J. Photochem. Photobiol. B: Biol. 151, 31-38.

(42)         Sadr-Arani, L., Mignon, P., Chermette, H. and Douki, T. (2014) Theoretical and experimental study of the fragmentation of protonated uracil. Chem. Phys. Lett. 605, 108-114.

(43)         Meador, J. A., Baldwin, A. J., Pakulski, J. D., Jeffrey, W. H., Mitchell, D. L. and Douki, T. (2014) The significance of the Dewar valence photoisomer as a UV radiation-induced DNA photoproduct in marine microbial communities. Environ. Microbiol. 16, 1808-1820.

(44)         Esposito, L., Banyasz, A., Douki, T., Perron, M., Markovitsi, D. and Improta, R. (2014) Effect of C5-Methylation of Cytosine on the Photoreactivity of DNA: A Joint Experimental and Computational Study of TCG Trinucleotides. J. Am. Chem. Soc. 136, 10838-10841.

(45)         Douki, T., Berard, I., Wack, A. and Andra, S. (2014) Contribution of Cytosine- Containing Cyclobutane Dimers to DNA Damage Produced by Photosensitized Triplet- Triplet Energy Transfer. Chem.-Eur. J. 20, 5787-5794.

(46)         Batal, M., Boudry, I., Mouret, S., Clery-Barraud, C., Wartelle, J., Berard, I. and Douki, T. (2014) DNA damage in internal organs after cutaneous exposure to sulphur mustard. Toxicol. Appl. Pharmacol. 278, 39-44.

(47)         Albarracin, V. H., Simon, J., Pathak, G. P., Valle, L., Douki, T., Cadet, J., Borsarelli, C. D., Farias, M. E. and Gartner, W. (2014) First characterisation of a CPD-class I photolyase from a UV-resistant extremophile isolated from High-Altitude Andean Lakes. Photochem. Photobiol. Sci. 13, 739-750.

(48)         Montillet, J. L., Leonhardt, N., Mondy, S., Tranchimand, S., Rumeau, D., Boudsocq, M., Garcia, A. V., Douki, T., Bigeard, J., Lauriere, C., Chevalier, A., Castresana, C. and Hirt, H. (2013) An Abscisic Acid-Independent Oxylipin Pathway Controls Stomatal Closure and Immune Defense in Arabidopsis. PLoS. Biol. 11, 15.

(49)         Labet, V., Jorge, N., Morell, C., Douki, T., Grand, A., Cadet, J. and Eriksson, L. A. (2013) UV-induced formation of the thymine-thymine pyrimidine (6-4) pyrimidone photoproduct - a DFT study of the oxetane intermediate ring opening. Photochem. Photobiol. Sci. 12, 1509-1516.

(50)         Jamin, E. L., Riu, A., Douki, T., Debrauwer, L., Cravedi, J. P., Zalko, D. and Audebert, M. (2013) Combined Genotoxic Effects of a Polycyclic Aromatic Hydrocarbon (B(a)P) and an Heterocyclic Amine (PhIP) in Relation to Colorectal Carcinogenesis. PLoS One 8, 11.

(51)         Genies, C., Maitre, A., Lefebvre, E., Jullien, A., Chopard-Lallier, M. and Douki, T. (2013) The Extreme Variety of Genotoxic Response to Benzo a pyrene in Three Different Human Cell Lines from Three Different Organs. PLoS One 8, 11.

(52)         Batal, M., Boudry, I., Mouret, S., Wartelle, J., Emorine, S., Bertoni, M., Berard, I., Clery-Barraud, C. and Douki, T. (2013) Temporal and spatial features of the formation of DNA adducts in sulfur mustard-exposed skin. Toxicol. Appl. Pharmacol. 273, 644-650.

(53)         Batal, M., Boudry, I., Clery-Barraud, C., Mouret, S. and Douki, T. (2013) Relative yields of monomeric and dimeric adducts induced by sulphur mustard in isolated and cellular DNA as determined by HPLC/tandem mass spectrometry. Toxicol Environ. Chem. 95, 260-276.

(54)         Wassmann, M., Moeller, R., Rabbow, E., Panitz, C., Horneck, G., Reitz, G., Douki, T., Cadet, J., Stan-Lotter, H., Cockell, C. S. and Rettberg, P. (2012) Survival of Spores of the UV-Resistant Bacillus subtilis Strain MW01 After Exposure to Low-Earth Orbit and Simulated Martian Conditions: Data from the Space Experiment ADAPT on EXPOSE-E. Astrobiology 12, 498.

(55)         Vaya, I., Gustavsson, T., Douki, T., Berlin, Y. and Markovitsi, D. (2012) Electronic: Excitation Energy Transfer between Nucleobases of Natural DNA. J. Am. Chem. Soc. 134, 11366-11368.

(56)         Perche-Letuvee, P., Kathirvelu, V., Berggren, G., Clemancey, M., Latour, J. M., Maurel, V., Douki, T., Armengaud, J., Mulliez, E., Fontecave, M., Garcia-Serres, R., Gambarelli, S. and Atta, M. (2012) 4-Demethylwyosine Synthase from Pyrococcus abyssi Is a Radical-S-adenosyl-L-methionine Enzyme with an Additional 4Fe-4S (+2) Cluster That Interacts with the Pyruvate Co-substrate. J. Biol. Chem. 287, 41174-41185.

(57)         Noonan, F. P., Zaidi, M. R., Wolnicka-Glubisz, A., Anver, M. R., Bahn, J., Wielgus, A., Cadet, J., Douki, T., Mouret, S., Tucker, M. A., Popratiloff, A., Merlino, G. and De Fabo, E. C. (2012) Melanoma induction by ultraviolet A but not ultraviolet B radiation requires melanin pigment. Nat. Commun. 3, 10.

(58)         Mouret, S., Forestier, A. and Douki, T. (2012) The specificity of UVA-induced DNA damage in human melanocytes. Photochem. Photobiol. Sci. 11, 155-162.

(59)         Jugan, M. L., Barillet, S., Simon-Deckers, A., Herlin-Boime, N., Sauvaigo, S., Douki, T. and Carriere, M. (2012) Titanium dioxide nanoparticles exhibit genotoxicity and impair DNA repair activity in A549 cells. Nanotoxicology 6, 501-513.

(60)         Horneck, G., Moeller, R., Cadet, J., Douki, T., Mancinelli, R. L., Nicholson, W. L., Panitz, C., Rabbow, E., Rettberg, P., Spry, A., Stackebrandt, E., Vaishampayan, P. and Venkateswaran, K. J. (2012) Resistance of Bacterial Endospores to Outer Space for Planetary Protection Purposes-Experiment PROTECT of the EXPOSE-E Mission. Astrobiology 12, 445-+.

(61)         Hanot, M., Boivin, A., Malesys, C., Beuve, M., Colliaux, A., Foray, N., Douki, T., Ardail, D. and Rodriguez-Lafrasse, C. (2012) Glutathione Depletion and Carbon Ion Radiation Potentiate Clustered DNA Lesions, Cell Death and Prevent Chromosomal Changes in Cancer Cells Progeny. PLoS One 7, 12.

(62)         Grand, A., Cadet, J., Eriksson, L. A., Labet, V., Jorge, N. L., Schreiber, M. L., Douki, T. and Morell, C. (2012) Comparison of the mechanism of deamination of 5,6-dihydro-5-methylcytosine with other cytosine derivatives. Theor. Chem. Acc. 131, 11.

(63)         Forestier, A., Douki, T., Sauvaigo, S., De Rosa, V., Demeilliers, C. and Rachidi, W. (2012) Alzheimer's Disease-Associated Neurotoxic Peptide Amyloid-B Impairs Base Excision Repair in Human Neuroblastoma Cells. Int. J. Mol. Sci. 13, 14766-14787.

(64)         de Rosa, V., Erkekoglu, P., Forestier, A., Favier, A., Hincal, F., Diamond, A. M., Douki, T. and Rachidi, W. (2012) Low doses of selenium specifically stimulate the repair of oxidative DNA damage in LNCaP prostate cancer cells. Free Radic. Res. 46, 105-115.

(65)         Banyasz, A., Douki, T., Improta, R., Gustavsson, T., Onidas, D., Vaya, I., Perron, M. and Markovitsi, D. (2012) Electronic Excited States Responsible for Dimer Formation upon UV Absorption Directly by Thymine Strands: Joint Experimental and Theoretical Study. J. Am. Chem. Soc. 134, 14834-14845.

(66)         Tarantini, A., Maitre, A., Lefebvre, E., Marques, M., Rajhi, A. and Douki, T. (2011) Polycyclic aromatic hydrocarbons in binary mixtures modulate the efficiency of benzo a pyrene to form DNA adducts in human cells. Toxicology 279, 36-44.

(67)         Tarantini, A., Douki, T., Personnaz, M. B., Besombes, J. L., Jafrezzo, J. L. and Maitre, A. (2011) Effect of the chemical composition of organic extracts from environmental and industrial atmospheric samples on the genotoxicity of polycyclic aromatic hydrocarbons mixtures. Toxicol Environ. Chem. 93, 941-954.

(68)         Nzengue, Y., Candeias, S. M., Sauvaigo, S., Douki, T., Favier, A., Rachidi, W. and Guiraud, P. (2011) The toxicity redox mechanisms of cadmium alone or together with copper and zinc homeostasis alteration: Its redox biomarkers. J. Trace Elem. Med. Biol. 25, 171-180.

(69)         Mouret, S., Leccia, M. T., Bourrain, J. L., Douki, T. and Beani, J. C. (2011) Individual Photosensitivity of Human Skin and UVA-Induced Pyrimidine Dimers in DNA. J. Invest. Dermatol. 131, 1539-1546.

(70)         Mouret, S., Bogdanowicz, P., Haure, M. J., Castex-Rizzi, N., Cadet, J., Favier, A. and Douki, T. (2011) Assessment of the Photoprotection Properties of Sunscreens by Chromatographic Measurement of DNA Damage in Skin Explants. Photochem. Photobiol. 87, 109-116.

(71)         McMahon, S. J., Hyland, W. B., Brun, E., Butterworth, K. T., Coulter, J. A., Douki, T., Hirst, D. G., Jain, S., Kavanagh, A. P., Krpetic, Z., Mendenhall, M. H., Muir, M. F., Prise, K. M., Requardt, H., Sanche, L., Schettino, G., Currell, F. J. and Sicard-Roselli, C. (2011) Energy Dependence of Gold Nanoparticle Radiosensitization in Plasmid DNA. J. Phys. Chem. C 115, 20160-20167.

(72)         Jugan, M. L., Barillet, S., Simon-Deckers, A., Sauvaigo, S., Douki, T., Herlin, N. and Carriere, M. (2011) Cytotoxic and Genotoxic Impact of TiO2 Nanoparticles on A549 Cells. J. Biomed. Nanotechnol. 7, 22-23.

(73)         du Puch, C. B. M., Barbier, E., Kraut, A., Coute, Y., Fuchs, J., Buhot, A., Livache, T., Seve, M., Favier, A., Douki, T., Gasparutto, D., Sauvaigo, S. and Breton, J. (2011) TOX4 and its binding partners recognize DNA adducts generated by platinum anticancer drugs. Arch. Biochem. Biophys. 507, 296-303.

(74)         Beblo, K., Douki, T., Schmalz, G., Rachel, R., Wirth, R., Huber, H., Reitz, G. and Rettberg, P. (2011) Survival of thermophilic and hyperthermophilic microorganisms after exposure to UV-C, ionizing radiation and desiccation. Arch. Microbiol. 193, 797-809.

(75)         Banyasz, A., Vaya, I., Changenet-Barret, P., Gustavsson, T., Douki, T. and Markovitsi, D. (2011) Base Pairing Enhances Fluorescence and Favors Cyclobutane Dimer Formation Induced upon Absorption of UVA Radiation by DNA. J. Am. Chem. Soc. 133, 5163-5165.

(76)         Amara, S., Douki, T., Garrel, C., Favier, A., Ben Rhouma, K., Sakly, M. and Abdelmelek, H. (2011) Effects of static magnetic field and cadmium on oxidative stress and DNA damage in rat cortex brain and hippocampus. Toxicol. Ind. Health 27, 99-106.

(77)         Vaya, I., Gustavsson, T., Miannay, F. A., Douki, T. and Markovitsi, D. (2010) Fluorescence of Natural DNA: From the Femtosecond to the Nanosecond Time Scales. J. Am. Chem. Soc. 132, 11834-11835.

(78)         Pierrel, F., Hamelin, O., Douki, T., Kieffer-Jaquinod, S., Muhlenhoff, U., Ozeir, M., Lill, R. and Fontecave, M. (2010) Involvement of Mitochondrial Ferredoxin and Para-Aminobenzoic Acid in Yeast Coenzyme Q Biosynthesis. Chem. Biol. 17, 449-459.

(79)         Obtulowicz, T., Winczura, A., Speina, E., Swoboda, M., Janik, J., Janowska, B., Ciesla, J. M., Kowalczyk, P., Jawien, A., Gackowski, D., Banaszkiewicz, Z., Krasnodebski, I., Chaber, A., Olinski, R., Nair, J., Bartsch, H., Douki, T., Cadet, J. and Tudek, B. (2010) Aberrant repair of etheno-DNA adducts in leukocytes and colon tissue of colon cancer patients. Free Radic. Biol. Med. 49, 1064-1071.

(80)         Mouret, S., Philippe, C., Gracia-Chantegrel, J., Banyasz, A., Karpati, S., Markovitsi, D. and Douki, T. (2010) UVA-induced cyclobutane pyrimidine dimers in DNA: a direct photochemical mechanism? Org. Biomol. Chem. 8, 1706-1711.

(81)         Moeller, R., Reitz, G., Douki, T., Cadet, J., Horneck, G. and Stan-Lotter, H. (2010) UV photoreactions of the extremely haloalkaliphilic euryarchaeon Natronomonas pharaonis. FEMS Microbiol. Ecol. 73, 271-277.

(82)         Moeller, R., Douki, T., Rettberg, P., Reitz, G., Cadet, J., Nicholson, W. L. and Horneck, G. (2010) Genomic bipyrimidine nucleotide frequency and microbial reactions to germicidal UV radiation. Arch. Microbiol. 192, 521-529.

(83)         McCullagh, M., Hariharan, M., Lewis, F. D., Markovitsi, D., Douki, T. and Schatz, G. C. (2010) Conformational Control of TT Dimerization in DNA Conjugates. A Molecular Dynamics Study. J. Phys. Chem. B 114, 5215-5221.

(84)         Matallana-Surget, S., Douki, T., Meador, J. A., Cavicchioli, R. and Joux, F. (2010) Influence of growth temperature and starvation state on survival and DNA damage induction in the marine bacterium Sphingopyxis alaskensis exposed to UV radiation. J. Photochem. Photobiol. B: Biol. 100, 51-56.

(85)         Labet, V., Morell, C., Douki, T., Cadet, J., Eriksson, L. A. and Grand, A. (2010) Hydrolytic Deamination of 5,6-Dihydrocytosine in a Protic Medium: A Theoretical Study. J. Phys. Chem. A 114, 1826-1834.

(86)         Asgatay, S., Martinez, A., Coantic-Castex, S., Harakat, D., Philippe, C., Douki, T. and Clivio, P. (2010) UV-Induced TA Photoproducts: Formation and Hydrolysis in Double-Stranded DNA. J. Am. Chem. Soc. 132, 10260-10261.

(87)         Arragain, S., Handelman, S. K., Forouhar, F., Wei, F. Y., Tomizawa, K., Hunt, J. F., Douki, T., Fontecave, M., Mulliez, E. and Atta, M. (2010) Identification of Eukaryotic and Prokaryotic Methylthiotransferase for Biosynthesis of 2-Methylthio-N-6-threonylcarbamoyladenosine in tRNA. J. Biol. Chem. 285, 28425-28433.

(88)         Arragain, S., Garcia-Serres, R., Blondin, G., Douki, T., Clemancey, M., Latour, J. M., Forouhar, F., Neely, H., Montelione, G. T., Hunt, J. F., Mulliez, E., Fontecave, M. and Atta, M. (2010) Post-translational Modification of Ribosomal Proteins: structural and functional characterization of rimo from thermotoga maritima, a radical s-adenosylmethionine methylthiotransferase. J. Biol. Chem. 285, 5792-5801.

(89)         Tarantini, A., Maitre, A., Lefebvre, E., Marques, M., Marie, C., Ravanat, J. L. and Douki, T. (2009) Relative contribution of DNA strand breaks and DNA adducts to the genotoxicity of benzo a pyrene as a pure compound and in complex mixtures. Mutat. Res. 671, 67-75.

(90)         Pilet, E., Nicolet, Y., Mathevon, C., Douki, T., Fontecilla-Camps, J. C. and Fontecave, M. (2009) The role of the maturase HydG in FeFe -hydrogenase active site synthesis and assembly. FEBS Lett. 583, 506-511.

(91)         Mitchell, D. L., Paniker, L. and Douki, T. (2009) DNA damage, repair and photoadaptation in a xiphophorus fish hybrid. Photochem. Photobiol. 85, 1384-1390.

(92)         Matallana-Surget, S., Douki, T., Cavicchioli, R. and Joux, F. (2009) Remarkable resistance to UVB of the marine bacterium Photobacterium angustum explained by an unexpected role of photolyase. Photochem. Photobiol. Sci. 8, 1313-1320.

(93)         Chater, S., Douki, T., Favier, A., Sakly, M. and Abdelmelek, H. (2009) Changes in antioxidant status and biochemical parameters after orally cadmium administration in females rats. Acta Biol. Hung. 60, 79-88.

(94)         Banyasz, A., Karpati, S., Lazzarotto, E., Markovitsi, D. and Douki, T. (2009) UV-induced structural changes of model DNA helices probed by optical spectroscopy. J. Phys. Chem. C 113, 11747-11750.

(95)         Amara, S., Douki, T., Garel, C., Favier, A., Sakly, M., Rhouma, K. B. and Abdelmelek, H. (2009) Effects of static magnetic field exposure on antioxidative enzymes activity and DNA in rat brain. Gen. Physiol. Biophys. 28, 260-265.

(96)         Rousselet, E., Richaud, P., Douki, T., Chantegrel, J. G., Favier, A., Bouron, A. and Moulis, J. M. (2008) A zinc-resistant human epithelial cell line is impaired in cadmium and manganese import. Toxicol. Appl. Pharmacol. 230, 312-319.

(97)         Mouret, S., Charveron, M., Favier, A., Cadet, J. and Douki, T. (2008) Differential repair of UVB-induced cyclobutane pyrimidine dimers in cultured human skin cells and whole human skin. DNA Repair 7, 704-712.

(98)         Millau, J. F., Raffin, A. L., Caillat, S., Claudet, C., Arras, G., Ugolin, N., Douki, T., Ravanat, J. L., Breton, J., Oddos, T., Dumontet, C., Sarasin, A., Chevillard, S., Favier, A. and Sauvaigo, S. (2008) A microarray to measure repair of damaged plasmids by cell lysates. Lab Chip 8, 1713-1722.

(99)         Matallana-Surget, S., Meador, J. A., Joux, F. and Douki, T. (2008) Effect of the GC content of DNA on the distribution of UVB-induced bipyrimidine photoproducts. Photochem. Photobiol. Sci. 7, 794-801.

(100)       Marie, C., Maitre, A., Douki, T., Gateau, M., Tarantini, A., Guiraud, P., Favier, A. and Ravanat, J. L. (2008) Influence of the metabolic properties of human cells on the kinetic of formation of the major benzo a pyrene DNA adducts. J. Appl. Toxicol. 28, 579-590.

(101)       Mantel, C., Chandor, A., Gasparutto, D., Douki, T., Atta, M., Fontecave, M., Bayle, P. A., Mouesca, J. M. and Bardet, M. (2008) Combined NMR and DFT studies for the absolute configuration elucidation of the spore photoproduct, a UV-induced DNA lesion. J. Am. Chem. Soc. 130, 16978-16984.

(102)       Girard, P. M., Pozzebon, M., Delacote, F., Douki, T., Smirnova, V. and Sage, E. (2008) Inhibition of S-phase progression triggered by UVA-induced ROS does not require a functional DNA damage checkpoint response in mammalian cells. DNA Repair 7, 1500-1516.

(103)       Ghosh, A., Joy, A., Schuster, G. B., Douki, T. and Cadet, J. (2008) Selective one-electron oxidation of duplex DNA oligomers: reaction at thymines. Org. Biomol. Chem. 6, 916-928.

(104)       Falletti, O. and Douki, T. (2008) Low glutathione level favors formation of DNA adducts to 4-hydroxy-2(E)-nonenal, a major lipid peroxidation product. Chem. Res. Toxicol. 21, 2097-2105.

(105)       Douki, T., Ksoury, Z., Marie, C., Favier, A., Ravanat, J. L. and Maitre, A. (2008) Genotoxicity of combined exposure to polycyclic aromatic hydrocarbons and UVA - A mechanistic study. Photochem. Photobiol. 84, 1133-1140.

(106)       Conan, P., Joux, F., Torreton, J. P., Pujo-Pay, M., Douki, T., Rochelle-Newall, E. and Mari, X. (2008) Effect of solar ultraviolet radiation on bacterio- and phytoplankton activity in a large coral reef lagoon (southwest New Caledonia). Aquat. Microb. Ecol. 52, 83-98.

(107)       Chater, S., Douki, T., Garrel, C., Favier, A., Sakly, M. and Abdelmelek, H. (2008) Cadmium-induced oxidative stress and DNA damage in kidney of pregnant female rats. C. R. Biol. 331, 426-432.

(108)       Chater, S., Douki, T., Favier, A., Garrel, C., Sakly, M. and Abdelmelek, H. (2008) Influence of static magnetic field on cadmium toxicity: study of oxidative stress and DNA damage in pregnant rat tissues. Electromagn. Biol. Med. 27, 393-401.

(109)       Chandor-Proust, A., Berteau, O., Douki, T., Gasparutto, D., Ollagnier-De-Choudens, S., Fontecave, M. and Atta, M. (2008) DNA repair and free radicals, new insights into the mechanism of spore photoproduct lyase revealed by single amino acid substitution. J. Biol. Chem. 283, 36361-36368.

(110)       Amara, S., Abdelmelek, H., Garrel, C., Guiraud, P., Douki, T., Ravanat, J. L., Favier, A., Sakly, M. and Ben Rhouma, K. (2008) Preventive effect of zinc against cadmium-induced oxidative stress in the rat testis. J. Reprod. Dev. 54, 129-134.

(111)       Moeller, R., Stackebrandt, E., Douki, T., Cadet, J., Rettberg, P., Mollenkopf, H. J., Reitz, G. and Horneck, G. (2007) DNA bipyrimidine photoproduct repair and transcriptional response of UV-C irradiated Bacillus subtilis. Arch. Microbiol. 188, 421-431.

(112)       Moeller, R., Douki, T., Cadet, J., Stackebrandt, E., Nicholson, W. L., Rettberg, P., Reitz, G. and Horneck, G. (2007) UV-radiation-induced formation of DNA bipyrimidine photoproducts in Bacillus subtilis endospores and their repair during germination. Int. Microbiol. 10, 39-46.

(113)       Garcin, G., Douki, T., Stoebner, P. E., Guesnet, J., Guezennec, A., Martinez, J., Cadet, J. and Meunier, L. (2007) Cell surface expression of melanocortin-1 receptor on HaCaT keratinocytes and alpha-melanocortin stimulation do not affect the formation and repair of UVB-induced DNA photoproducts. Photochem. Photobiol. Sci. 6, 585-593.

(114)       Falletti, O., Cadet, J., Favier, A. and Douki, T. (2007) Trapping of 4-hydroxynonenal by glutathione efficiently prevents formation of DNA adducts in human cells. Free Radic. Biol. Med. 42, 1258-1269.

(115)       Chandor, A., Douki, T., Gasparutto, D., Gambarelli, S., Sanakis, Y., Nicolet, Y., Ollagnier-De-Choudens, S., Atta, M. and Fontecave, M. (2007) Characterization of the DNA repair spore photoproduct lyase enzyme from Clostridium acetobutylicum: A radical-SAM enzyme. C. R. Chim. 10, 756-765.

(116)       Amara, S., Douki, T., Ravanat, J. L., Garrel, C., Guiraud, P., Favier, A., Sakly, M., Ben Rhouma, K. and Abdelmelek, H. (2007) Influence of a static magnetic field (250 mT) on the antioxidant response and DNA integrity in THP1 cells. Phys. Med. Biol. 52, 889-898.

(117)       Amara, S., Abdelmelek, H., Garrel, C., Guiraud, P., Douki, T., Ravanat, J. L., Favier, A., Sakly, M. and Ben Rhouma, K. (2007) Zinc supplementation ameliorates static magnetic field-induced oxidative stress in rat tissues. Environ. Toxicol. Pharmacol. 23, 193-197.

(118)       Voituron, Y., Servais, S., Romestaing, C., Douki, T. and Barre, H. (2006) Oxidative DNA damage and antioxidant defenses in the European common lizard (Lacerta vivipara) in supercooled and frozen states. Cryobiology 52, 74-82.

(119)       Valton, J., Fontecave, M., Douki, T., Kendrew, S. G. and Niviere, V. (2006) An aromatic hydroxylation reaction catalyzed by a two-component FMN-dependent monooxygenase - The ActVA-ActVB system from streptomyces coelicolor. J. Biol. Chem. 281, 27-35.

(120)       Mouret, S., Baudouin, C., Charveron, M., Favier, A., Cadet, J. and Douki, T. (2006) Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation. Proc. Natl. Acad. Sci. U. S. A. 103, 13765-13770.

(121)       Hazane, F., Sauvaigo, S., Douki, T., Favier, A. and Beani, J. C. (2006) Age-dependent DNA repair and cell cycle distribution of human skin fibroblasts in response to UVA irradiation. J. Photochem. Photobiol. B: Biol. 82, 214-223.

(122)       Dubois, P., Marchand, G., Fouillet, Y., Berthier, J., Douki, T., Hassine, F., Gmouh, S. and Vaultier, M. (2006) Ionic liquid droplet as e-microreactor. Anal. Chem. 78, 4909-4917.

(123)       Douki, T., Ravanat, J. L., Pouget, J. P., Testard, I. and Cadet, J. (2006) Minor contribution of direct ionization to DNA base damage induced by heavy ions. Int. J. Radiat. Biol. 82, 119-127.

(124)       Douki, T. (2006) Low ionic strength reduces cytosine photoreactivity in UVC-irradiated isolated DNA. Photochem. Photobiol. Sci. 5, 1045-1051.

(125)       Douki, T. (2006) Effect of denaturation on the photochemistry of pyrimidine bases in isolated DNA. J. Photochem. Photobiol. B: Biol. 82, 45-52.

(126)       Davoine, C., Falletti, O., Douki, T., Iacazio, G., Ennar, N., Montillet, J. L. and Triantaphylides, C. (2006) Adducts of oxylipin electrophiles to glutathione reflect a 13 specificity of the downstream lipoxygenase pathway in the tobacco hypersensitive response. Plant Physiol. 140, 1484-1493.

(127)       Daghino, S., Turci, F., Tomatis, M., Favier, A., Perotto, S., Douki, T. and Fubini, B. (2006) Soil fungi reduce the iron content and the DNA damaging effects of asbestos fibers. Environ. Sci. Technol. 40, 5793-5798.

(128)       Chater, S., Abdelmelek, H., Douki, T., Garrel, C., Favier, A., Sakly, M. and Ben Rhouma, K. (2006) Exposure to static magnetic field of pregnant rats induces hepatic GSH elevation but not oxidative DNA damage in liver and kidney. Arch. Med. Res. 37, 941-946.

(129)       Chandor, A., Berteau, O., Douki, T., Gasparutto, D., Sanakis, Y., Ollagnier-De-Choudens, S., Atta, M. and Fontecave, M. (2006) Dinucleotide spore photoproduct, a minimal substrate of the DNA repair spore photoproduct lyase enzyme from Bacillus subtilis. J. Biol. Chem. 281, 26922-26931.

(130)       Amara, S., Abdelmelek, H., Garrel, C., Guiraud, P., Douki, T., Ravanat, J. L., Favier, A., Sakly, M. and Ben Rhouma, K. (2006) Effects of subchronic exposure to static magnetic field on testicular function in rats. Arch. Med. Res. 37, 947-952.

(131)       Amara, S., Abdelmelek, H., Garrel, C., Guiraud, P., Douki, T., Ravanat, J. L., Favier, A., Sakly, M. and Ben Rhouma, K. (2006) Influence of static magnetic field on cadmium toxicity: Study of oxidative stress and DNA damage in rat tissues. J. Trace Elem. Med. Biol. 20, 263-269.

(132)       Seve, M., Chimienti, F., Devargnas, S., Aouffen, M., Douki, T., Chantegrel, J., Cadet, J. and Favier, A. (2005) Resveratrol enhances UVA-induced DNA damage in HaCat human keratinocytes. Medicinal Chemistry 1, 623-633.

(133)       Servais, S., Boussouar, A., Molnar, A., Douki, T., Pequignot, J. M. and Favier, R. (2005) Age-related sensitivity to lung oxidative stress during ozone exposure. Free Radic. Res. 39, 305-316.

(134)       Guerniou, V., Gasparutto, D., Douki, T., Cadet, J. and Sauvaigo, S. (2005) Enhancement of the in vitro transcription by T7 RNA polymerase of short DNA templates containing oxidative thymine lesions. C. R. Biol. 328, 794-801.

(135)       Gedik, C. M., Collins, A., Dubois, J., Duez, P., Kouegnigan, L., Rees, J. F., Loft, S., Moller, P., Jensen, A., Poulsen, H., Riss, B., Weimann, A., Cadet, J., Douki, T., Ravant, J. L., Sauvaigo, S., Faure, H., Morel, I., Morin, B., Epe, B., Eckert, I., Hartwig, A., Schwerdtle, T., Dolara, P., Giovannelli, L., Lodovici, M., Guglielmi, F., Olinski, R., Bialkowski, K., Foksinski, M., Gackowski, D., Durackova, Z., Muchova, J., Korytar, P., Sivonova, M., Dusinska, M., Mislanova, C., Petrovska, H., Smolkova, B., Vina, J., Lloret, A., Saez, G., Moller, L., Hofer, T., Eriksson, H., Gremaud, E., Herbert, K., Wild, C., Kelly, F., Dunster, C., White, A., Wood, S., Vaughan, N. and Escodd. (2005) Establishing the background level of base oxidation in human lymphocyte DNA: results of an interlaboratory validation study. Faseb J. 19, 82-84.

(136)       Douki, T., Setlow, B. and Setlow, P. (2005) Effects of the binding of a/b-type small, acid-soluble spore proteins on the photochemistry of DNA in spores of Bacillus subtilis and in vitro. Photochem. Photobiol. 81, 163-169.

(137)       Douki, T., Setlow, B. and Setlow, P. (2005) Photosensitization of DNA by dipicolinic acid, a major component of spores of Bacillus species. Photochem. Photobiol. Sci. 4, 591-597.

(138)       De la Vega, U. P., Rettberg, P., Douki, T., Cadet, J. and Horneck, G. (2005) Sensitivity to polychromatic UV-radiation of strains of Deinococcus radiodurans differing in their DNA repair capacity. Int. J. Radiat. Biol. 81, 601-611.

(139)       Davoine, C., Douki, T., Iacazio, G., Montillet, J. L. and Triantaphylides, C. (2005) Conjugation of keto fatty acids to glutathione in plant tissues. Characterization and quantification by HPLC-tandem mass spectrometry. Anal. Chem. 77, 7366-7372.

(140)       Courdavault, S., Baudouin, C., Charveron, M., Canguilhem, B., Favier, A., Cadet, J. and Douki, T. (2005) Repair of the three main types of bipyrimidine DNA photoproducts in human keratinocytes exposed to UVB and UVA radiations. DNA Repair 4, 836-844.

(141)       Pierrel, F., Douki, T., Fontecave, M. and Atta, M. (2004) MiaB protein is a bifunctional radical-S-adenosylmethionine enzyme involved in thiolation and methylation of tRNA. J. Biol. Chem. 279, 47555-47563.

(142)       Montillet, J. L., Cacas, J. L., Garnier, L., Montane, M. H., Douki, T., Bessoule, J. J., Polkowska-Kowalczyk, L., Maciejewska, U., Agnel, J. P., Vial, A. and Triantaphylides, C. (2004) The upstream oxylipin profile of Arabidopsis thaliana: a tool to scan for oxidative stresses. Plant J. 40, 439-451.

(143)       Douki, T., Odin, F., Caillat, S., Favier, A. and Cadet, J. (2004) Predominance of the 1,N2-propano 2 '-deoxyguanosine adduct among 4-hydroxy-2-nonenal-induced DNA lesions. Free Radic. Biol. Med. 37, 62-70.

(144)       Courdavault, S., Baudouin, C., Sauvaigo, S., Mouret, S., Candeias, S., Charveron, M., Favier, A., Cadet, J. and Douki, T. (2004) Unrepaired cyclobutane pyrimidine dimers do not prevent proliferation of UV-B-irradiated cultured human fibroblasts. Photochem. Photobiol. 79, 145-151.

(145)       Courdavault, S., Baudouin, C., Charveron, M., Favier, A., Cadet, J. and Douki, T. (2004) Larger yield of cyclobutane dimers than 8-oxo-7,8-dihydroguanine in the DNA of UVA-irradiated human skin cells. Mutat. Res. 556, 135-142.

(146)       Chazal, M., Roux, E., Alapetite, C., Roulin, C., Moustacchi, E., Douki, T., Baudouin, C., Charveron, M. and Basset-Seguin, N. (2004) Interexperimental and interindividual variations of DNA repair capacities after UV-13 and UV-C irradiations of human keratinocytes and fibroblasts. Photochem. Photobiol. 79, 286-290.

(147)       Frelon, S., Douki, T., Favier, A. and Cadet, J. (2003) Hydroxyl radical is not the main reactive species involved in the degradation of DNA bases by copper in the presence of hydrogen peroxide. Chem. Res. Toxicol. 16, 191-197.

(148)       Douki, T., Vadesne-Bauer, G. and Cadet, J. (2003) Formation of a methide derivative upon photolysis of thymidine bromohydrins. J. Org. Chem. 68, 478-482.

(149)       Douki, T., Reynaud-Angelin, A., Cadet, J. and Sage, E. (2003) Bipyrimidine photoproducts rather than oxidative lesions are the main type of DNA damage involved in the genotoxic effect of solar UVA radiation. Biochemistry 42, 9221-9226.

(150)       Douki, T., Laporte, G. and Cadet, J. (2003) Inter-strand photoproducts are produced in high yield within A-DNA exposed to UVC radiation. Nucleic Acids Res. 31, 3134-3142.

(151)       Douki, T. and Cadet, J. (2003) Formation of the spore photoproduct and other dimeric lesions between adjacent pyrimidines in UVC-irradiated dry DNA. Photochem. Photobiol. Sci. 2, 433-436.

(152)       Collins, A., Gedik, C., Vaughan, N., Wood, S., White, A., Dubois, J., Rees, J. F., Loft, S., Moller, P., Cadet, J., Douki, T., Ravanat, J. L., Sauvaigo, S., Faure, H., Morel, I., Morin, M., Epe, B., Phoa, N., Hartwig, A., Schwerdtle, T., Dolara, P., Giovannelli, L., Lodovici, M., Olinski, R., Bialkowski, K., Foksinski, M., Gackowski, D., Durackova, Z., Hlincikova, L., Korytar, P., Sivonova, M., Dusinska, M., Mislanova, C., Vina, J., Moller, L., Hofer, T., Nygren, J., Gremaud, E., Herbert, K., Lunec, J., Wild, C., Hardie, L., Olliver, J., Smith, E. and Escodd. (2003) Measurement of DNA oxidation in human cells by chromatographic and enzymic methods. Free Radic. Biol. Med. 34, 1089-1099.

(153)       Riis, B., Collins, A., Gedik, C., Vaughan, N., Wood, S., White, A., Dubois, J., Duez, P., Dehon, G., Rees, J. F., Loft, S., Moller, P., Poulsen, H., Weimann, A., Cadet, J., Douki, T., Ravanat, J. L., Sauvaigo, S., Faure, H., Morel, I., Morin, B., Epe, B., Phoa, N., Hartwig, A., Pelzer, A., Dolara, P., Casalini, C., Giovannelli, L., Lodovici, M., Olinski, R., Bialkowski, K., Foksinski, M., Gackowski, D., Durackova, Z., Hlincikova, L., Korytar, P., Sivonova, M., Dusinska, M., Mislanova, C., Vina, J., Lloret, A., Moller, L., Hofer, T., Nygren, J., Gremaud, E., Herbert, K., Chauhan, D., Kelly, F., Dunster, C., Lunec, J., Cooke, M., Evans, M., Patel, P., Podmore, I., White, A., Wild, C., Hardie, L., Olliver, J. and Smith, E. (2002) Comparison of results from different laboratories in measuring 8-oxo-2'-deoxyguanosine in synthetic oligonucleotides. Free Radic. Res. 36, 649-659.

(154)       Ravanat, J. L., Douki, T., Duez, P., Gremaud, E., Herbert, K., Hofer, T., Lasserre, L., Saint-Pierre, C., Favier, A. and Cadet, J. (2002) Cellular background level of 8-oxo-7,8-dihydro-2 '-deoxyguanosine: an isotope based method to evaluate artefactual oxidation of DNA during its extraction and subsequent work-up. Carcinogenesis 23, 1911-1918.

(155)       Lindqvist, L., Czochralska, B., Fontaine-Aupart, M. P., Kawczynski, W., Tfibel, F. and Douki, T. (2002) Photochemistry of 2-chloropyrimidine. Photochem. Photobiol. Sci. 1, 600-606.

(156)       Frelon, S., Douki, T., Favier, A. and Cadet, J. (2002) Comparative study of base damage induced by gamma radiation and Fenton reaction in isolated DNA. J. Chem. Soc.-Perkin Trans. 1, 2866-2870.

(157)       Frelon, S., Douki, T. and Cadet, J. (2002) Radical oxidation of the adenine moiety of nucleoside and DNA: 2-hydroxy-2 '-deoxyadenosine is a minor decomposition product. Free Radic. Res. 36, 499-508.

(158)       Douki, T., Vadesne-Bauer, G. and Cadet, J. (2002) Formation of 2 '-deoxyuridine hydrates upon exposure of nucleosides to gamma radiation and UVC-irradiation of isolated and cellular DNA. Photochem. Photobiol. Sci. 1, 565-569.

(159)       Douki, T., Riviere, J. and Cadet, J. (2002) DNA tandem lesions containing 8-oxo-7,8-dihydroguanine and formamido residues arise from intramolecular addition of thymine peroxyl radical to guanine. Chem. Res. Toxicol. 15, 445-454.

(160)       Collins, A. R., Gedik, C., Wood, S., White, A., Dubois, J., Duez, P., Rees, J. F., Legall, R., Degand, L., Loft, S., Jensen, A., Poulsen, H., Weimann, A., Jensen, B. R., Cadet, J., Douki, T., Ravanat, J. L., Faure, H., Tripier, M., Morel, I., Sergent, O., Cillard, P., Morin, B., Epe, B., Phoa, N., Hartwig, A., Pelzer, A., Dolara, P., Casalini, C., Guglielmi, F., Luceri, C., Kasai, H., Kido, R., Olinski, R., Bialkowski, K., Durackova, Z., Hlincikova, L., Korytar, P., Dusinska, M., Mislanova, C., Vina, J., Lloret, A., Moller, L., Hofer, T., Gremaud, E., Fay, L., Stadler, R., Eakins, J., Pognan, F., O'Brien, J., Elliott, R., Astley, S., Bailley, A., Herbert, K., Chauhan, D., Kelly, F., Dunster, C., Lunec, J., Podmore, I., Patel, P., Johnson, S., Evans, M., White, A., Tyrrell, R., Gordon, M., Wild, C., Hardie, L., Smith, E. and Escodd. (2002) Inter-laboratory validation of procedures for measuring 8-oxo-7,8-dihydroguanine/8-oxo-7,8-dihydro-2 '-deoxyguanosine in DNA. Free Radic. Res. 36, 239-245.

(161)       Collins, A., Gedik, C., Vaughan, N., Wood, S., White, A., Dubois, J., Duez, P., Dehon, G., Rees, J. F., Loft, S., Moller, P., Poulsen, H., Riis, B., Weimann, A., Cadet, J., Douki, T., Ravanat, J. L., Sauvaigo, S., Faure, H., Morel, I., Morin, B., Epe, B., Phoa, N., Hartwig, A., Pelzer, A., Dolara, P., Casalini, C., Giovannelli, L., Lodovici, M., Olinski, R., Bialkowski, K., Foksinski, M., Gackowski, D., Durackova, Z., Hlincikova, L., Korytar, P., Sivonova, M., Dusinska, M., Mislanova, C., Vina, J., Lloret, A., Moller, L., Hofer, T., Nygren, J., Gremaud, E., Herbert, K., Chauhan, D., Kelly, F., Dunster, C., Lunec, J., Cooke, M., Evans, M., Patel, P., Podmore, I., White, A., Wild, C., Hardie, L., Olliver, J., Smith, E. and Oxidati, E. E. S. C. (2002) Comparative analysis of baseline 8-oxo-7,8-dihydroguanine in mammalian cell DNA, by different methods in different laboratories: an approach to consensus. Carcinogenesis 23, 2129-2133.

(162)       Sauvaigo, S., Douki, T., Odin, F., Caillat, S., Ravanat, J. L. and Cadet, J. (2001) Analysis of fluoroquinolone-mediated photosensitization of 2'-deoxyguanosine, calf thymus and cellular DNA: Determination of Type-I, Type-II and triplet-triplet energy transfer mechanism contribution. Photochem. Photobiol. 73, 230-237.

(163)       Douki, T. and Cadet, J. (2001) Individual determination of the yield of the main UV-induced dimeric pyrimidine photoproducts in DNA suggests a high mutagenicity of CC photolesions. Biochemistry 40, 2495-2501.

(164)       Douki, T., Angelov, D. and Cadet, J. (2001) UV laser photolysis of DNA: Effect of duplex stability on charge-transfer efficiency. J. Am. Chem. Soc. 123, 11360-11366.

(165)       Dany, A. L., Douki, T., Triantaphylides, C. and Cadet, J. (2001) Repair of the main UV-induced thymine dimeric lesions within Arabidopsis thaliana DNA: evidence for the major involvement of photoreactivation pathways. J. Photochem. Photobiol. B: Biol. 65, 127-135.

(166)       Barraud, L., Douki, T., Guerret, S., Chevallier, M., Jamard, C., Trepo, C., Wild, C. P., Cadet, J. and Cova, L. (2001) The role of duck hepatitis B virus and aflatoxin B-1 in the induction of oxidative stress in the liver. Cancer Detect. Prev. 25, 192-201.

(167)       Pouget, J. P., Douki, T., Richard, M. J. and Cadet, J. (2000) DNA damage induced in cells by gamma and UVA radiation as measured by HPLC/GC-MS and HPLC-EC and comet assay. Chem. Res. Toxicol. 13, 541-549.

(168)       Frelon, S., Douki, T., Ravanat, J. L., Pouget, J. P., Tornabene, C. and Cadet, J. (2000) High-performance liquid chromatography-tandem mass spectrometry measurement of radiation-induced base damage to isolated and cellular DNA. Chem. Res. Toxicol. 13, 1002-1010.

(169)       Douki, T., Court, M., Sauvaigo, S., Odin, F. and Cadet, J. (2000) Formation of the main UV-induced thymine dimeric lesions within isolated and cellular DNA as measured by high performance liquid chromatography-tandem mass spectrometry. J. Biol. Chem. 275, 11678-11685.

(170)       Douki, T., Bretonniere, Y. and Cadet, J. (2000) Protection against radiation-induced degradation of DNA bases by polyamines. Radiat. Res. 153, 29-35.

(171)       Di Mascio, P., Teixeira, P. C., Onuki, J., Medeiros, M. H. G., Dornemann, D., Douki, T. and Cadet, J. (2000) DNA damage by 5-aminolevulinic and 4,5-dioxovaleric acids in the presence of ferritin. Arch. Biochem. Biophys. 373, 368-374.

(172)       Collins, A. R., Brown, J., Bogdanov, M., Cadet, J., Cooke, M., Douki, T., Dunster, C., Eakins, J., Epe, B., Evans, M., Farmer, P., Gedik, C. M., Halliwell, B., Herbert, K., Hofer, T., Hutchinson, R., Jenner, A., Jones, G. D. D., Kasai, H., Kelly, F., Lloret, A., Loft, S., Lunec, J., McEwan, M., Moller, L., Olinski, R., Podmore, I., Poulsen, H., Ravanat, J. L., Rees, J. F., Reetz, F., Shertzer, H., Spiegelhalder, B., Turesky, R., Tyrrell, R., Vina, J., Vinicombe, D., Weimann, A., de Wergifosse, B., Wood, S. G. and Escodd. (2000) Comparison of different methods of measuring 8-oxoguanine as a marker of oxidative DNA damage. Free Radic. Res. 32, 333-341.

(173)       Bourdat, A. G., Douki, T., Frelon, S., Gasparutto, D. and Cadet, J. (2000) Tandem base lesions are generated by hydroxyl radical within isolated DNA in aerated aqueous solution. J. Am. Chem. Soc. 122, 4549-4556.

(174)       Bianchini, F., Elmstahl, S., Martinez-Garcia, C., van Kappel, A. L., Douki, T., Cadet, J., Ohshima, H., Riboli, E. and Kaaks, R. (2000) Oxidative DNA damage in human lymphocytes: correlations with plasma levels of alpha-tocopherol and carotenoids. Carcinogenesis 21, 321-324.

(175)       Arimoto-Kobayashi, S., Anma, N., Yoshinaga, Y., Douki, T., Cadet, J. and Hayatsu, H. (2000) Oxidative damage and induced mutations in M13mp2 phage DNA exposed to N-nitrosopyrrolidine with UVA radiation. Mutagenesis 15, 473-477.

(176)       Tremblay, S., Douki, T., Cadet, J. and Wagner, J. R. (1999) 2 '-deoxycytidine glycols, a missing link in the free radical-mediated oxidation of DNA. J. Biol. Chem. 274, 20833-20838.

(177)       Pouget, J. P., Ravanat, J. L., Douki, T., Richard, M. J. and Cadet, J. (1999) Measurement of DNA base damage in cells exposed to low doses of gamma-radiation: comparison between the HPLC-EC and comet assays. Int. J. Radiat. Biol. 75, 51-58.

(178)       Douki, T., Spinelli, S., Ravanat, J. L. and Cadet, J. (1999) Hydroxyl radical-induced degradation of 2 '-deoxyguanosine under reducing conditions. J. Chem. Soc.-Perkin Trans. 2, 1875-1880.

(179)       Douki, T., Perdiz, D., Grof, P., Kuluncsics, Z., Moustacchi, E., Cadet, J. and Sage, E. (1999) Oxidation of guanine in cellular DNA by solar UV radiation: Biological role. Photochem. Photobiol. 70, 184-190.

(180)       Douki, T. and Cadet, J. (1999) Modification of DNA bases by photosensitized one-electron oxidation. Int. J. Radiat. Biol. 75, 571-581.

(181)       Ravanat, J. L., Duretz, B., Guiller, A., Douki, T. and Cadet, J. (1998) Isotope dilution high-performance liquid chromatography - electrospray tandem mass spectrometry assay for the measurement of 8-oxo-7,8-dihydro-2 '-deoxyguanosine in biological samples. J. Chromatogr. B 715, 349-356.

(182)       Douki, T., Onuki, J., Medeiros, M. H. G., Bechara, E. J. H., Cadet, J. and Di Mascio, P. (1998) DNA alkylation by 4,5-dioxovaleric acid, the final oxidation product of 5-aminolevulinic acid. Chem. Res. Toxicol. 11, 150-157.

(183)       Douki, T., Onuki, J., Medeiros, M. H. G., Bechara, E. J. H., Cadet, J. and Di Mascio, P. (1998) Hydroxyl radicals are involved in the oxidation of isolated and cellular DNA bases by 4-aminolevulinic acid. FEBS Lett. 428, 93-96.

(184)       Delatour, T., Douki, T., Gasparutto, D., Brochier, M. C. and Cadet, J. (1998) A novel vicinal lesion obtained from the oxidative photosensitization of TpdG: Characterization and mechanistic aspects. Chem. Res. Toxicol. 11, 1005-1013.

(185)       Delatour, T., Douki, T., D'Ham, C. and Cadet, J. (1998) Photosensitization of thymine nucleobase by benzophenone through energy transfer, hydrogen abstraction and one-electron oxidation. J. Photochem. Photobiol. B: Biol. 44, 191-198.

(186)       Carvalho, V. M., Di Mascio, P., Campos, I. P. D., Douki, T., Cadet, J. and Medeiros, M. H. G. (1998) Formation of 1,N6-etheno-2 '-deoxyadenosine adducts by trans,trans-2,4-decadienal. Chem. Res. Toxicol. 11, 1042-1047.

(187)       Douki, T., Zalizniak, T. and Cadet, J. (1997) Far-UV-induced dimeric photoproducts in short oligonucleotides: Sequence effects. Photochem. Photobiol. 66, 171-179.

(188)       Douki, T., Martini, R., Ravanat, J. L., Turesky, R. J. and Cadet, J. (1997) Measurement of 2,6-diamino-4-hydroxy-5-formamidopyrimidine and 8-oxo-7,8-dihydroguanine in isolated DNA exposed to gamma radiation in aqueous solution. Carcinogenesis 18, 2385-2391.

(189)       Faure, H., Coudray, C., Mousseau, M., Ducros, V., Douki, T., Bianchini, F., Cadet, J. and Favier, A. (1996) 5-hydroxymethyluracil excretion, plasma Tbars and plasma antioxidant vitamins in adriamycin-treated patients. Free Radic. Biol. Med. 20, 979-983.

(190)       Douki, T., Delatour, T., Paganon, F. and Cadet, J. (1996) Measurement of oxidative damage at pyrimidine bases in gamma-irradiated DNA. Chem. Res. Toxicol. 9, 1145-1151.

(191)       Douki, T., Delatour, T., Bianchini, F. and Cadet, J. (1996) Observation and prevention of an artefactual formation of oxidized DNA bases and nucleosides in the GC-EIMS method. Carcinogenesis 17, 347-353.

(192)       Douki, T., Cadet, J. and Ames, B. N. (1996) An adduct between peroxynitrite and 2'-deoxyguanosine: 4,5-dihydro-5-hydroxy-4-(nitrosooxy)-2'-deoxyguanosine. Chem. Res. Toxicol. 9, 3-7.

(193)       Douki, T. and Cadet, J. (1996) Peroxynitrite mediated oxidation of purine bases of nucleosides and isolated DNA. Free Radic. Res. 24, 369-380.

(194)       Douki, T., Voituriez, L. and Cadet, J. (1995) Measurement of pyrimidine(6-4) photoproducts in DNA by a mild acidic hydrolysis hplc fluorescence detection assay. Chem. Res. Toxicol. 8, 244-253.

(195)       Douki, T. and Cadet, J. (1994) Formation of cyclobutane dimers and (6-4)-photoproducts upon far-UV photolysis of 5-methylcytosine-containing dinucleoside monophosphates. Biochemistry 33, 11942-11950.

(196)       Douki, T. and Ames, B. N. (1994) An HPLC-EC assay for 1,N2-propano adducts of 2'-deoxyguanosine with 4-hydroxynonenal and other alpha,beta-unsaturated aldehydes. Chem. Res. Toxicol. 7, 511-518.

(197)       Blais, J., Douki, T., Vigny, P. and Cadet, J. (1994) Fluorescence quantum yield determination of pyrimidine(6-4) pyrimidone photoadducts. Photochem. Photobiol. 59, 402-404.

(198)       Ravanat, J. L., Douki, T., Incardona, M. F. and Cadet, J. (1993) HPLC separations of normal and modified nucleobases and nucleosides on an amino silica-gel column. J. Liq. Chromatogr. 16, 3185-3202.

(199)       Douki, T. and Cadet, J. (1992) Far-UV photochemistry and photosensitization of 2'-deoxycytidylyl-(3'-5')-thymidine - Isolation and characterization of the main photoproducts. J. Photochem. Photobiol. B: Biol. 15, 199-213.

(200)       Douki, T., Voituriez, L. and Cadet, J. (1991) Characterization of the (6-4) photoproduct of 2'-deoxycytidylyl-(3'-5')-thymidine and of its Dewar valence isomer. Photochem. Photobiol. 53, 293-297.

 

2. Review Article

(1)           Douki, T. (2020) Oxidative Stress and Genotoxicity in Melanoma Induction: Impact on Repair Rather Than Formation of DNA Damage? Photochem Photobiol.

(2)           Carriere, M., Arnal, M. E. and Douki, T. (2020) TiO2 genotoxicity: An update of the results published over the last six years. Mutat Res 854-855, 503198.

(3)           Cadet, J. and Douki, T. (2018) Formation of UV-induced DNA damage contributing to skin cancer development. Photochem. Photobiol. Sci. 17, 1816-1841.

(4)           Douki, T., von Koschembahr, A. and Cadet, J. (2017) Insight in DNA repair of UV-induced pyrimidine dimers by chromatographic methods. Photochem. Photobiol. 93, 207-215.

(5)           Carriere, M., Sauvaigo, S., Douki, T. and Ravanat, J. L. (2017) Impact of nanoparticles on DNA repair processes: current knowledge and working hypotheses. Mutagenesis 32, 203-213.

(6)           Ravanat, J. L. and Douki, T. (2016) UV and ionizing radiations induced DNA damage, differences and similarities. Radiat. Phys. Chem. 128, 92-102.

(7)           Douki, T. and Sage, E. (2016) Dewar valence isomers, the third type of environmentally relevant DNA photoproducts induced by solar radiation. Photochem. Photobiol. Sci. 15, 24-30.

(8)           Cadet, J., Douki, T. and Ravanat, J. L. (2015) Oxidatively Generated Damage to Cellular DNA by UVB and UVA Radiation. Photochem. Photobiol. 91, 140-155.

(9)           Ravanat, J. L., Breton, J., Douki, T., Gasparutto, D., Grand, A., Rachidi, W. and Sauvaigo, S. (2014) Radiation-mediated formation of complex damage to DNA: a chemical aspect overview. Br. J. Radiol. 87, 6.

(10)         Genies, C., Maître, A., Tarantini, A. and Douki, T. (2014) Evaluation in vitro de la génotoxicité des hydrocarbures aromatiques polycycliques purs ou en mélange. Environ. Risques Santé 13, 318-324.

(11)         Douki, T. (2013) The variety of UV-induced pyrimidine dimeric photoproducts in DNA as shown by chromatographic quantification methods. Photochem. Photobiol. Sci. 12, 1286-1302.

(12)         Cadet, J., Douki, T., Ravanat, J. L. and Wagner, J. R. (2013) Measurement of oxidatively generated base damage to nucleic acids in cells: facts and artifacts. Bioanalytical Reviews 4, 55-74.

(13)         Ravanat, J. L., Cadet, J. and Douki, T. (2012) Oxidatively Generated DNA Lesions as Potential Biomarkers of In Vivo Oxidative Stress. Curr. Mol. Med. 12, 655-671.

(14)         Cadet, J., Mouret, S., Ravanat, J. L. and Douki, T. (2012) Photoinduced Damage to Cellular DNA: Direct and Photosensitized Reactions. Photochem. Photobiol. 88, 1048-1065.

(15)         Cadet, J., Douki, T. and Ravanat, J. L. (2011) Measurement of oxidatively generated base damage in cellular DNA. Mutat. Res. 711, 3-12.

(16)         Cadet, J. and Douki, T. (2011) Oxidatively Generated Damage to DNA by UVA Radiation in Cells and Human Skin. J. Invest. Dermatol. 131, 1005-1007.

(17)         Douki, T. (2010) Thymine cyclobutane dimers: the most frequent ans persistent DNA lesions in skin exposed to both UVB and UVA. Expert Rev. Dermatol. 5, 649-657.

(18)         Cadet, J., Douki, T. and Ravanat, J. L. (2010) Oxidatively generated base damage to cellular DNA. Free Radic. Biol. Med. 49, 9-21.

(19)         Douki, T., Ravanat, J. L., Saint-Pierre, C., Gasparutto, D., Favier, A. and Cadet, J. (2009) La spectrométrie de masse : un outil remarquanble pour l'étude des dommages de l'ADN. Spectra Analyse 271, 20-25.

(20)         Cadet, J., Douki, T., Ravanat, J. L. and Di Mascio, P. (2009) Sensitized formation of oxidatively generated damage to cellular DNA by UVA radiation. Photochem. Photobiol. Sci. 8, 903-911.

(21)         Cadet, J., Douki, T. and Ravanat, J. L. (2008) Oxidatively generated damage to the guanine moiety of DNA: Mechanistic aspects and formation in cells. Accounts Chem. Res. 41, 1075-1083.

(22)         Cadet, J., Douki, T. and Ravanat, J. L. (2006) One-electron oxidation of DNA and inflammation processes. Nat. Chem. Biol. 2, 348-349.

(23)         Cadet, J., Sage, E. and Douki, T. (2005) Ultraviolet radiation-mediated damage to cellular DNA. Mutat. Res. 571, 3-17.

(24)         Cadet, J., Douki, T., Gasparutto, D. and Ravanat, J. L. (2005) Radiation-induced damage to cellular DNA: measurement and biological role. Radiat. Phys. Chem. 72, 293-299.

(25)         Cadet, J., Bellon, S., Douki, T., Frelon, S., Gasparutto, D., Muller, E., Pouget, J. P., Ravanat, J. L., Romieu, A. and Sauvaigo, S. (2004) Radiation-induced DNA damage: formation, measurement, and biological features. J. Environ. Pathol. Toxicol. Oncol. 23, 33-43.

(26)         Onuki, J., Teixeira, P. C., Medeiros, M. H. G., dornemann, D., Douki, T., Cadet, J. and Di Mascio, P. (2002) Is 5-aminolevulinic acid involved in the hepatocellular carcinogenesis of accute intermittent porphyria? Cell. Mol. Biol. 48, 17-26.

(27)         Cadet, J., Douki, T., Gasparutto, D., Ravanat, J. L. and Sauvaigo, S. (2002) Les lésions radio-induites de l'ADN. Médecine Nucléaire 26, 119-125.

(28)         Cadet, J., Douki, T., Frelon, S., Sauvaigo, S., Pouget, J. P. and Ravanat, J. L. (2002) Assessment of oxidative base damage to isolated and cellular DNA by HPLC-MS/MS measurement. Free Radic. Biol. Med. 33, 441-449.

(29)         Cadet, J., Bellon, S., Berger, M., Bourdat, A. G., Douki, T., Duarte, V., Frelon, S., Gasparutto, D., Muller, E., Ravanat, J. L. and Sauvaigo, S. (2002) Recent aspects of oxidative DNA damage: Guanine lesions, measurement and substrate specificity of DNA repair glycosylases. Biol. Chem. 383, 933-943.

(30)         Ravanat, J. L., Douki, T. and Cadet, J. (2001) Direct and indirect effects of UV radiation on DNA and its components. J. Photochem. Photobiol. B: Biol. 63, 88-102.

(31)         Cadet, J., Berger, M., Bourdat, A. G., Douki, T., Duarte, V., Gasparutto, D., Pouget, J. P., ravanat, J. L. and Sauvaigo, S. (2001) Oxidative base damage to DNA: formation, role of metals and measurement. L'Anteneo 19, 39-41.

(32)         Cadet, J., Douki, T., Pouget, J. P. and Ravanat, J. L. (2000) Singlet oxygen DNA damage products: Formation and measurement. Methods Enzymol. 319, 143-153.

(33)         Cadet, J., Delatour, T., Douki, T., Gasparutto, D., Pouget, J. P., Ravanat, J. L. and Sauvaigo, S. (1999) Hydroxyl radicals and DNA base damage. Mutat. Res. 424, 9-21.

(34)         Poulsen, H. E., Weimann, A., Salonen, J. T., Nyyssonen, K., Loft, S., Cadet, J., Douki, T. and Ravanat, J. L. (1998) Does vitamin C have a pro-oxidant effect? Nature 395, 231-232.

(35)         Cadet, J., D'Ham, C., Douki, T., Pouget, J. P., Ravanat, J. L. and Sauvaigo, S. (1998) Facts and artifacts in the measurement of oxidative base damage to DNA. Free Radic. Res. 29, 541-550.

(36)         Cadet, J., Douki, T. and Ravanat, J. L. (1997) Artifacts associated with the measurement of oxidized DNA bases. Environ. Health Perspect. 105, 1034-1039.

(37)         Cadet, J., Berger, M., Douki, T. and Ravanat, J.-L. (1997) Oxidative damage to DNA: formation , measurement and biological significance. Reviews Physiol. Biochem. Pharmacol. 131, 1-87.

(38)         Cadet, J., Berger, M., Douki, T., Morin, B., Raoul, S., Ravanat, J. L. and Spinelli, S. (1997) Effects of UV and visible radiation on DNA - Final base damage. Biol. Chem. 378, 1275-1286.

(39)         Cadet, J., Anselmino, C., Douki, T. and Voituriez, L. (1992) Photochemistry of nucleic-acids in cells. J. Photochem. Photobiol. B: Biol. 15, 277-298.

(40)         Douki, T., Voituriez, L., L.-S., K. and Cadet, J. (1990) Pyrimidine (6-4) pyrimidone photoadducts: formation, chemical and photochemical properties. The Spectrum 3, 9-12.

 

3. Book Chapters

(1)           Douki, T. (2016) Sunlight-induced DNA damage: molecular mechanisms and photoprotection strategies, In Skin Stress Response Pathways: Environmental Factors and Molecular Opportunities (Wondrak, G. T., Ed.) pp 49-77, Springer Int. Publish.

(2)           Cadet, J., Grand, A. and Douki, T. (2015) Solar UV Radiation-Induced DNA Bipyrimidine Photoproducts: Formation and Mechanistic Insights, In Photoinduced Phenomena in Nucleic Acids Ii: DNA Fragments and Phenomenological Aspects (Barbatti, M., Borin, A. C. and Ullrich, S., Eds.) pp 249-275, Springer-Verlag Berlin, Berlin.

(3)           Cadet, J., Douki, T., Ravanat, J.-L. and Di Mascio, P. (2015) Reactions of singlet oxygen with nucleic Acids, In Singlet Oxygen: Applications in Biosciences and Nanosciences (Nonell, S., Ed.), RSC publisher.

(4)           Douki, T. and Ravanat, J.-L. (2014) Quantification of DNA damage using mass spectrometry techniques, In Nucleic Acids in the Gas Phase (Gabelica, V., Ed.) pp 203-234, Springer.

(5)           Cadet, J., Douki, T., Ravanat, J. L. and Wagner, J. R. (2013) Measurement of oxidatively generated base damage to nucleic acids in cells: facts and artifacts, In Frontiers of Bioanalytical Chemistry (Matysik, F.-M. and Wegener, J., Eds.) p 269, Springer.

(6)           Douki, T. (2010) Formation and repair of UV-induced DNA damage, In Handbook Organic Photochemistry and Photobiology (Ghetti, F., Ed.) pp 1349-1392, CRC Publications.

(7)           Cadet, J. and Douki, T. (2010) Molecular effects of UV and ionizing radiation, In Origins and Evolution of Life  pp 359-374, Cambridge University Press.

(8)           Cadet, J., Douki, T., Gasparutto, D., Ravanat, J.-L. and Wagner, J. R. (2009) Chemical reactions of the radical cations of nucleobases in isolated and cellular DNA. Formation of single lesions, In Radicals in Nucleic Acids (Greenberg, M. C., Ed.) pp 70-99, Wiley & Sons.

(9)           Douki, T. and Cadet, J. (2008) Radiation-induced damage to DNA: from model compounds to cell, In Radiation chemistry: from basics to applications in materials and life sciences (Spotheim-Maurizot, M., Mostafavi, M., Douki, T. and Belloni, J., Eds.) pp 183-196, EDP Sciences, Paris.

(10)         Douki, T. (2007) UV induced DNA damage, In Biophysical and physiological effects of solar radiation on human skin (Giacomoni, P. U., Ed.) pp 227-269, RCS Publishing.

(11)         Sage, E., Perdiz, D., Grof, P., Reynaud-Angelin, A., Douki, T., Cadet, J., Rochette, P., Bastien, N. and Drouin, R. (2005) DNA damage induced by UVA radiation: role in solar mutagenesis, In From DNA Photolesions to Mutations, Skin Cancer and Cell Death, Royal Society of Chemistry Publishing, Cambridge, UK.

(12)         Badouard, C., Douki, T., Faure, P., Halimi, S., Cadet, J., Favier, A. and Ravanat, J.-L. (2005) DNA lesions as biomarkers of inflammation and oxidative stress: a preliminary evaluation, In Free Radicals and Diseases: Gene Expression, Cellular Metabolism and Pathophysiology (Grune, T., Ed.) pp 1-8, IOS Press.

(13)         Douki, T., Ravanat, J. L., Angelov, D., Wagner, J. R. and Cadet, J. (2004) Effects of duplex stability on charge-transfer efficiency within DNA, In Long-Range Charge Transfer in DNA I  pp 1-25, Springer-Verlag Berlin.

(14)         Cadet, J., Douki, T. and Sauvaigo, S. (2004) Effets oxydants des radiations ionisantes et de la lumière UV solaire sur l'ADN cellulaire, In Les Cahiers des Clubs Ecrin : Pratiques Scientifiques et Maîtrise de l'Environnement (Roigny, P., Ed.) pp 171-186.

(15)         Cadet, J., Douki, T. and Ravanat, J.-L. (2003) The human genome as a target of oxidative modification: damage to nucleic acids, In Redox-Genome Interactions in Health and Disease (Fuchs, J., Podda, M. and Packer, L., Eds.) pp 145-192, Marcel Dekker Inc., New-York.

(16)         Cadet, J., Douki, T. and Ravanat, J.-L. (2002) Radiation, In Encyclopedia of Molecular Medecine  pp 2717-2720, Wyley and Sons, Inc. .

(17)         Ravanat, J.-L., Douki, T. and Cadet, J. (2001) Photochemistry of nucleic acid, In Sun Protection for Human. (Giacomoni, P. U., Ed.) pp 207-230.

(18)         Douki, T., Ravanat, J.-L., Frelon, S., Bourdat, A. G., Pouget, J. P. and Cadet, J. (2001) HPLC-MS/MS measurement of oxidative base damage to isolated and cellular DNA, In Oxidative stress and aging: diagnostics, intervention and longevity  pp 190-202.

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(22)         Cadet, J., Bardet, M., Berger, M., Bourdat, A. G., Douki, T., Duarte, V., Frelon, S., Gasparutto, D., Grand, A., Pouget, J. P., Ravanat, J.-L., Signorini, N. and Sauvaigo, S. (2000) Oxidative damage to DNA: Measurement and biological role, In Free Radicals In Chemistry, Biology And Medecine (Yoshikawa, T., Toyokuni, S., Yamamoto, Y. and Naito , Y., Eds.) pp 45-56, Oica International, London.

(23)         Cadet, J., Carvalho, V. M., Onuki, J., Douki, T., Medeiros, M. H. G. and Di Mascio, P. (1999) Purine DNA adducts of 4,5-dioxovaleric acid and 2,4-decadienal, In Exocyclic DNA Adducts in Mutagenesis and Carcinogenesis (Singer, B. and Bartsch, H., Eds.) pp 103-113, Int Agency Research Cancer, Lyons.

(24)         Cadet, J., Bardet, M., Delatour, T., Douki, T., Gasparutto, D., Molko, D., Pouget, J. P., Ravanat, J. L., Signorini, N. and Sauvaigo, S. (1999) Radiation chemistry of DNA. Damage induced by ionizing and UV radiations, In Fundamentals for the Assessment of Risks from Environmental Radiation (BaumstarkKhan, C., Kozubek, S. and Horneck, G., Eds.) pp 91-102, Springer, Dordrecht.

(25)         Cadet, J., Bardet, M., Berger, M., Berthod, T., Delatour, T., D'Ham, C., Douki, T., Gasparutto, D., Grand, A., Guy, A., Jolibois, F., Molko, D., Polverelli, M., Ravanat, J. L., Romieu, A., Signorini, N. and Sauvaigo, S. (1999) Oxidative base damage to DNA - Recent mechanistic aspects, measurement and repair, In Advances in DNA Damage and Repair: Oxygen Radical Effects, Cellular Protection, and Biological Consequences (Dizdaroglu, M. and Karakaya, A. E., Eds.) pp 47-58, Plenum Press Div Plenum Publishing Corp, New York.

(26)         Douki, T., Ravanat, J. L. and Cadet, J. (1998) Measurement of oxidized bases in DNA and biological fluids by gas chromatography coupled to mass spectrometry, In Handbook of clinical analysis; In vivo oxidative damage to biomolecules (Grifiths, H. R. and Lunec, J., Eds.) pp 15-26.

(27)         Douki, T. and Cadet, J. (1995) UV and nucleic acids, In Interface between chemistry and biochemistry (Jörnvall, H. and Jollès, P., Eds.) pp 173-197, Birkhaüser Verlag AG, Basel, Switzerland.

(28)         Douki, T., Berger, M., Raoul, S., Ravanat, J. L. and Cadet, J. (1995) Determination of 8-oxopurines in DNA by HPLC using amperometric detection, In Analysis of Free Radicals in Biological Systems (Favier, A., Ed.) pp 213-224, Birkaüser Verlag, Basel, Basel, Switzerland.

(29)         Cadet, J., Berger, M., Buchko, G., Douki, T., Incardona, M. F., Morin, B., Raoul, S., Ravanat, J. L. and Voituriez, L. (1995) Photochemical and radical induced damage to DNA, In Ozone Sun Cancer: Molecular and Cellular Mechanisms Prevention (Dubertret, L., Santus, R. and Morliere, P., Eds.) pp 51-54, Editions Inserm, Paris.

(30)         Cadet, J., Berger, M., Douki, T., Voituriez, L., Angelov, D. and Vigny, P. (1992) DNA base damage induced by ultraviolet radiations, In Selected Topics in Photobiology (Jain, V. and Goel, H., Eds.) pp 36-50, Indian Photobiology Society, New Dehli.